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- $Unique_ID{BRK03840}
- $Pretitle{}
- $Title{Hyperhidrosis}
- $Subject{Hyperhidrosis Bromhidrosis Hemihyperhidrosis Excessive Perspiration
- Excessive Sweating }
- $Volume{}
- $Log{}
-
- Copyright (C) 1986, 1992 National Organization for Rare Disorders, Inc.
-
- 216:
- Hyperhidrosis
-
- ** IMPORTANT **
- It is possible the main title of the article (Hyperhidrosis) is not the
- name you expected. Please check the SYNONYMS listing to find the alternate
- names and disorder subdivisions covered by this article.
-
- Synonyms
-
- Bromhidrosis
- Hemihyperhidrosis
- Excessive Perspiration
- Excessive Sweating
-
- General Discussion
-
- ** REMINDER **
- The information contained in the Rare Disease Database is provided for
- educational purposes only. It should not be used for diagnostic or treatment
- purposes. If you wish to obtain more information about this disorder, please
- contact your personal physician and/or the agencies listed in the "Resources"
- section of this report.
-
-
- Hyperhidrosis (excessive sweating) may be confined to certain areas of
- the body or may affect the entire body. When the entire body is affected the
- eccrine sweat glands cause the problem, while the localized type is produced
- by apocrine sweat glands. When Hyperhidrosis is localized it usually affects
- the palms, soles, underarms, the area under the breasts, or the groin.
-
- Symptoms
-
- Hyperhidrosis is characterized by excessive sweating, either over the entire
- body or on the palms, soles, armpits (axilla), the area under the breasts, or
- the groin area. Onset usually occurs in childhood or during puberty. The
- skin in the affected areas is often pink or bluish white. In severe cases
- the skin, especially on the feet, may be softened by the moisture
- (macerated), cracked, or scaling. The perspiration may have a bad odor
- (Bromhidrosis). This odor is caused by a chemical breakdown of the sweat and
- cellular debris by bacteria and yeasts.
-
- Generalized Hyperhidrosis, which affects the entire body, frequently
- accompanies fever.
-
- Hyperhidrosis sometimes improves spontaneously around the age of 25
- years.
-
- Causes
-
- Improper functioning of endocrine glands such as the thyroid
- (hyperthyroidism), pituitary gland, or occasionally a central nervous system
- disorder, may cause generalized Hyperhidrosis.
-
- The cause of localized Hyperhidrosis is not known. This type of
- excessive sweating usually occurs in otherwise normal individuals.
- Hyperhidrosis of the palms and soles may be triggered by emotion or exercise.
- As with normal sweating, Hyperhidrosis may be precipitated by heat, either
- from outside the body or from a fever. The sweating may also be caused by
- illnesses or disorders such as infection, diabetes mellitus, tumors, gout,
- menopause and alcohol intoxication.
-
- Certain foods such as garlic may cause the odor of the perspiration
- (Bromhidrosis) to intensify.
-
- For more information on Hyperhidrosis, see "Sweating It Out: The Problem
- of Perfuse Perspiration" in the Prevalent Health Conditions/Concerns area of
- NORD Services (RDB-10).
-
- Related Disorders
-
- Frey's Syndrome (Gustatory Hyperhidrosis) is a type of excessive sweating
- triggered by eating or drinking spicy foods and beverages. This type of
- hyperhidrotic attack may occur in otherwise healthy people, especially on the
- face. Frey's Syndrome can sometimes be caused by a tumor, mumps, or surgery
- to the salivary gland near the ear (the parotid salivary gland). This may be
- due to dysfunction of common sympathetic nerves projecting to both the
- salivary glands and affected sweat glands. Thus sweating rather than
- salivating may occur. (For more information, choose "Frey" as your search
- term in the Rare Disease Database.)
-
- Affected Population
-
- Onset of Hyperhidrosis is usually during childhood or adolescence. The
- disorder affects both males and females from all ethnic groups equally.
-
- Therapies: Standard
-
- For people who have Hyperhidrosis of palms and soles (palmar-plantar type
- Hyperhidrosis), wearing cotton socks and shoes that let air circulate is
- helpful in preventing overheating of the feet. Rotating shoes daily is also
- recommended.
-
- The use of medicated powder that inhibits bacterial growth and absorbs
- moisture may be helpful. Cornstarch is not recommended.
-
- For persistent cases of Hyperhidrosis, several topical agents (e.g.,
- aluminum chloride in ethyl alcohol) may be prescribed by a dermatologist.
- Menopausal sweating is usually treated with estrogen.
-
- Anticholinergic drugs may also be prescribed in severe cases for short
- term treatment of Hyperhidrosis. However, side effects such as dry mouth,
- drowsiness, and constipation often make use of these drugs problematic.
-
- In the most extreme and disabling cases surgical removal of the sweat
- glands from the armpits may be performed. However, scarring may occur as a
- result of the operation.
-
- Another surgical procedure to treat the most severe cases of
- Hyperhidrosis is severing of the sympathetic nerve that connects the sweat
- glands to the central nervous system (sympathectomy). However, the excessive
- sweating never disappears completely, and a fair amount of patients have
- recurrences of hyperhidrotic symptoms. Horner's Syndrome, in which nerve
- paralysis results in drooping of the eyelids, may be a complication of
- sympathectomy.
-
- Biofeedback has been used with varying degrees of success in some cases.
- A patient can learn to exert control over a physical function such as
- sweating with a biofeedback machine that monitors and registers the effects
- of that function.
-
- Therapies: Investigational
-
- A device that uses iontophoresis, in which charged atoms (ions) are
- electrically driven into the skin, is being used experimentally to treat
- Hyperhidrosis.
-
- This disease entry is based upon medical information available through
- August 1992. Since NORD's resources are limited, it is not possible to keep
- every entry in the Rare Disease Database completely current and accurate.
- Please check with the agencies listed in the Resources section for the most
- current information about this disorder.
-
- Resources
-
- For more information on Hyperhidrosis, please contact:
-
- National Organization for Rare Disorders (NORD)
- P.O. Box 8923
- New Fairfield, CT 06812-1783
- (203) 746-6518
-
- National Digestive Diseases Information Clearinghouse
- Box NDDIC
- Bethesda, MD 20892
- (301) 468-6344
-
- References
-
- SWEATING IT OUT: THE PROBLEM OF PROFUSE PERSPIRATION: Dixie Farley; FDA
- Consumer (December 1985-January 1986). Pp. 21-25.
-
-